I'm in Pfizer's COVID vaccine trial, ask me anything.

[sniper97]

I have not been vaccinated. I had covid end of July 2020. With my next post, there are successful early treatments available that are being ignored. This is the 1st mRNA vaccine ever, I would rather wait. Could there be long term affects? Just had a friend get vaccinated and he was in the hospital for 3-4 days, at one point he was told he had lymphoma.

[sniper97]

https://www.hsgac.senate.gov/hearing...id-19-solution

Senate hearing 11/20, pre Thanksgiving, biggest concern, why are early treatment options not used?

[Brokeass_baller]

Yeah, I don't understand the mask thing at all. If the vax works, then who cares about the unvaccinated?

I'm not anti-vax at all. But there have been some really crazy side-effects associated with this mRNA one that makes me hesitant. I'm just sort of watching the public for the time being. Not to mention, I've made it this far without catching covid. So, do I really need it? Maybe I'll regret that in the future. I don't know. I'm just watching right now.

[BrickHaus]

Im with Lew, the level of sociteial pressure to get this vaccine is unreal. I feel it is great that its now readily avialable, and if you feel you need it go get it, it seems pretty easy to do.


But the fact that its being pushed that EVERYONE NEEDS to get it, is crazy to me. The radio ads, and larg corperation inscentives are equaply unnerving.

I could take my point a few directions from here as I see this whole situation odd, and uncomforting. But I generally dont trust doctors, not only have they proven to simply be product pushers for big pharma(see the opoid crisis we face as a society), they have their own court system in which they can only be taken into litigation through, so good luck suing them when they are neglegant, and ruin your life. I dont get a flu shot, why would I get this new unvetted flu shot?

To me, this is the largest scale clinical trial for the drug companies to ever take place, and people are signing up in droves to get on board. Im worried we are going to see a wave of side effects from this, but long term slowly developing issues. Stuff like cancer, and random infections that arent going ro show theie heads for years to come.

So Id rather personally take my chances with the virus that has a 1% kill rate, vs the vaccine that isnt clinically tested. But the fact that unvaccinated people are told to continue wearing masks is only proving to be punishme t to try to force more vaccines.

At this point, in the U.S., we have 2 types of people, vavcinated people ( supposedly immune and free to run around) and people willing to take the risk, so why the need to keep putting one of those in groups down?

And sorry for my rant. As someone whos worn a mask for 10+ hours a day, 5 days a week at work, Im pretty burnt out on this whole thing. My work has recently allowed unvaccinated people to remove their masks, but threatened termination if unvaccinated people remove their masks. I dont understand it. Feels pretty discriminitory to me, and the tone of society isnt helping. Im just burnt out on this hyper fearmongering crusade.

[lew]

I've got a question for you, and I intend only for level-headed debate: Why is this vaccine necessary?

[lhamilton1807]

I had a couple of covid doh! Moments last week.

One was when my brother in law gave me the vaccine argument that " it has been proven to alter your DNA." Well that's the point, to alter your DNA before the virus does it for you. Even the flu alters your DNA.

The other was a news article about why older vaccinated people are still dying of covid. They are immuno compromised in the first place, and the vaccine doesn't generate a response.

Those are interesting topics. I’m not sure the flu alters your DNA - you might want to check on that. I’m pretty sure you’re still genetically unchanged after you get sick with something. Only bacteria actually store viral code in their DNA. We just store antibodies for a while as instructions on what to do if virus X or Y shows up.

I’ve not heard of consistent breakthrough cases - do you have a link to that article? I’d be very interested in reading about that. From what I’ve read, the vaccines don’t make us immortal, they just reduce (not eliminate) the risk of contracting COVID-19, or if you catch it they reduce the severity of the disease. We can still die of other things that are either pre-existing or unrelated.

[Diomedes]

Yeah, mRNA vaccines literally can't affect your own DNA. There RNA doesn't even get into the nucleus! And our cells don't have the integrases and reverse transcriptases needed to take exogenous RNA and insert it into our own DNA.

There *are* viruses that do that. TONS of them. HIV, Epstein-Barr, HPV...it's a long list. But coronaviruses do not, influenzaviruses do not, and none of these vaccines do.

H1N1 is an interesting case: We actually have samples of the original viruses from 1918, isolated from corpses buried in permafrost. And then of course we have samples of all the flus *after* 1918. That's when we were like 'huh, maybe we should be keeping track somehow'. So because we have those 1918 samples, we can follow that specific lineage's evolution over the last century.

[Brokeass_baller]

Does cDNA play a role here? Like, I know AIDS can do something with it. I keep hearing that the shot affects DNA, but I don't see how, knowing that mRNA can't act in reverse and enter the chromosome.

[Spider!]

I guess I'm actually thinking of white blood cell programming, specifically. My father's GB treatment left him with a genetic leukemia marker that they figured out was not actually his.

[Spider!]

So how do they track mutations in h1n1 95 years back?

Also, while not a direct effect of the flu, isn't Guillain-Barre syndrome a genetic alteration?

[Diomedes]

Well...no. Neither any COVID vaccine nor any flu virus nor any flu vaccine alters your DNA. What all vaccines do in trigger an immune response, which amplifies the number of a specific subset of cells that are compatible with the pathogen in question. But none of it alters your DNA. Only a handful of viruses (retroviruses, like HIV, for example), can actually change your DNA. Coronaviruses and influenza viruses cannot.

[Diomedes]

There have been an elevated number of reported cases of myocarditis and pericarditis. As is often the case, CDC is a great source: https://www.cdc.gov/coronavirus/2019...ocarditis.html

It's worth nothing that the vaccine adverse reaction reporting system (VAERS) are self-reported, and the number of confirmed cases is quite low compared to the number of reported cases. For confirmed cases, treatment has been very effective, with few if any long-term effects.

The takeaway is that even if there is a causal relationship between the vaccine and either condition, vaccination is still the lower-risk course of action.

[Spider!]

I had a couple of covid doh! Moments last week.

One was when my brother in law gave me the vaccine argument that " it has been proven to alter your DNA." Well that's the point, to alter your DNA before the virus does it for you. Even the flu alters your DNA.

The other was a news article about why older vaccinated people are still dying of covid. They are immuno compromised in the first place, and the vaccine doesn't generate a response.

[Axel]

I'll let you know if I grow any extra digits

[sniper97]

https://www.reuters.com/world/middle...es-2021-06-01/

I did find this.